Having played piano, harmonica, and reeded wind instruments for many years, I found the melodica super easy to play.

My mother had one of these way back in the day, and I used to love playing with it

While I'd never played one before, and am not a musician, I can play a pretty decent blues harmonica and started to learn guitar about three years ago (and am doing pretty well playing rhythm).

She enjoys playing music using a couple of keyboard apps on her tablet